Jason Klein is the Senior Vice President and CIO at Memorial Sloan-Kettering Cancer Center, where he oversees the hospital’s $4.5 billion in long-term investment assets. Jason has spent the last decade and a half overseeing endowment pools – 9 at MSKCC and 5 at the Museum of Modern Art. Jason got his start in the investment business learning the tools of private equity, and had training as an investment banker, management consultant, and lawyer.

Our conversation starts with the distinctive features that drive the investment structure for Memorial Sloan Kettering and flows through core beliefs, asset allocation frameworks and manager selection. Aspects of his due diligence process, including 30 questions and pre-mortem analysis, offer new arrows to an allocator’s quiver to those in previous conversations. Jason’s curiosity and eagerness to ask questions provides a terrific structure for applying capital allocation to a distinctive pool of capital.