Josh Wolfe is the co-founder of Lux Capital, a $1.5 billion venture capital firm that targets cutting-edge solutions to the most vexing puzzles of our time. Josh is an innovative thinker, whose ideas have found their way to columns in Forbes, lectures at MIT, Harvard, Yale, Columbia, and NYU and storms on Twitter.

Our conversation covers Josh’s early passion for science and finance, building a competitive advantage in venture capital from scratch, the full-blown investment process at Lux, including sourcing ideas, conducting due diligence, making investment decisions, constructing portfolios, and exiting companies, navigating a challenging private equity environment, posting on Twitter, active vs. passive management, dinner table conversation, and life lessons.